Lars Køber Selected Research

Mineralocorticoid Receptor Antagonists

11/2023	Sacubitril/valsartan compared to ramipril in high-risk post-myocardial infarction patients stratified according to use of mineralocorticoid receptor antagonists: Insight from the PARADISE MI trial.
1/2023	Initiation of eplerenone or spironolactone, treatment adherence, and associated outcomes in patients with new-onset heart failure with reduced ejection fraction: a nationwide cohort study.
8/2021	Developing and validating models to predict sudden death and pump failure death in patients with heart failure and preserved ejection fraction.
1/2021	Effects of dapagliflozin in heart failure with reduced ejection fraction and chronic obstructive pulmonary disease: an analysis of DAPA-HF.
12/2019	Sex-Related Differences in Heart Failure With Preserved Ejection Fraction.
1/2019	N-Terminal Pro-B-Type Natriuretic Peptide Levels for Risk Prediction in Patients With Heart Failure and Preserved Ejection Fraction According to Atrial Fibrillation Status.
1/2017	Declining Risk of Sudden Death in Heart Failure.
7/2016	A randomized controlled study of finerenone vs. eplerenone in patients with worsening chronic heart failure and diabetes mellitus and/or chronic kidney disease.
2/2015	Rationale and design of MinerAlocorticoid Receptor antagonist Tolerability Study-Heart Failure (ARTS-HF): a randomized study of finerenone vs. eplerenone in patients who have worsening chronic heart failure with diabetes and/or chronic kidney disease.

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Lars Køber Research Topics

Disease

250	Heart Failure 05/2024 - 01/2002
141	Myocardial Infarction 03/2024 - 08/2002
73	Atrial Fibrillation 02/2024 - 01/2002
64	ST Elevation Myocardial Infarction 03/2024 - 04/2006
59	Stroke (Strokes) 05/2024 - 04/2010
44	Out-of-Hospital Cardiac Arrest 11/2023 - 08/2010
41	Type 2 Diabetes Mellitus (MODY) 06/2024 - 02/2010
34	Left Ventricular Dysfunction 03/2024 - 05/2003
34	Hemorrhage 01/2024 - 12/2009
32	Cardiovascular Diseases (Cardiovascular Disease) 03/2024 - 06/2006
29	Infarction (Infarctions) 01/2023 - 09/2004
25	Systolic Heart Failure 01/2024 - 01/2011
25	Cardiac Arrhythmias (Arrythmia) 01/2023 - 03/2002
22	Hypertension (High Blood Pressure) 07/2023 - 05/2004
19	Heart Arrest (Cardiac Arrest) 03/2024 - 08/2009
19	Chronic Obstructive Pulmonary Disease (COPD) 01/2023 - 10/2011
18	Cardiomyopathies (Cardiomyopathy) 05/2024 - 03/2014
17	Ischemic Stroke 10/2022 - 09/2013
16	Endocarditis 05/2024 - 01/2009
15	Chronic Renal Insufficiency 01/2024 - 04/2012
15	Aortic Valve Stenosis (Aortic Stenosis) 11/2023 - 08/2011
14	Coronary Artery Disease (Coronary Atherosclerosis) 01/2024 - 03/2004
12	Acute Coronary Syndrome 12/2023 - 02/2005
12	Diabetes Mellitus 01/2023 - 09/2004
11	Heart Diseases (Heart Disease) 10/2023 - 09/2003
11	Thromboembolism 01/2021 - 08/2012
10	Infections 05/2024 - 10/2011
10	COVID-19 05/2023 - 07/2020
9	Neoplasms (Cancer) 11/2023 - 01/2012
9	Thrombosis (Thrombus) 01/2023 - 09/2008
9	Sudden Death 01/2021 - 01/2002
9	Myocardial Ischemia (Ischemic Heart Diseases) 10/2018 - 02/2005
9	Coma (Comas) 01/2018 - 12/2012
8	Human Influenza (Influenza) 05/2024 - 02/2021
8	Chronic Kidney Failure (Chronic Renal Failure) 10/2023 - 01/2016
7	Frailty 04/2024 - 01/2018
7	Inflammation (Inflammations) 07/2023 - 03/2019
7	Cardiac Sudden Death (Sudden Cardiac Arrest) 01/2023 - 01/2011
7	Insulin Resistance 01/2023 - 10/2003
7	Overweight 01/2020 - 08/2009
6	Ventricular Tachycardia 03/2024 - 09/2007

Drug/Important Bio-Agent (IBA)

51	dapagliflozinIBA 05/2024 - 01/2019
38	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 03/2024 - 11/2003
35	Brain Natriuretic Peptide (Natrecor)FDA Link 05/2024 - 05/2004
27	Glucose (Dextrose)FDA LinkGeneric 11/2023 - 11/2004
27	pro-brain natriuretic peptide (1-76)IBA 10/2023 - 02/2005
18	SodiumIBA 03/2024 - 11/2011
18	Biomarkers (Surrogate Marker)IBA 01/2023 - 10/2011
17	sacubitril and valsartan sodium hydrate drug combinationIBA 03/2024 - 01/2017
17	AnticoagulantsIBA 02/2024 - 04/2014
17	Clopidogrel (Plavix)FDA Link 11/2023 - 12/2009
17	omega-Chloroacetophenone (Mace)IBA 11/2023 - 02/2013
17	Vitamin K FDA Link 01/2023 - 10/2002
15	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 11/2023 - 08/2005
15	DiureticsIBA 01/2023 - 08/2011
15	Valsartan (Vals)FDA Link 01/2022 - 11/2003
15	DiamondIBA 05/2011 - 03/2002
14	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 01/2023 - 06/2006
14	Natriuretic PeptidesIBA 01/2023 - 05/2004
14	Insulin (Novolin)FDA Link 11/2022 - 03/2004
13	empagliflozinIBA 02/2024 - 06/2019
13	Sodium-Glucose Transporter 2 InhibitorsIBA 02/2024 - 01/2019
13	TroponinIBA 10/2023 - 10/2012
12	Sodium-Glucose Transport ProteinsIBA 02/2024 - 06/2019
12	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 12/2022 - 12/2009
12	dofetilide (Tikosyn)FDA Link 05/2011 - 01/2002
11	GadoliniumIBA 11/2023 - 01/2016
10	Warfarin (Coumadin)FDA LinkGeneric 02/2024 - 09/2010
10	Ezetimibe (Zetia)FDA Link 02/2015 - 08/2011
10	Simvastatin (Zocor)FDA LinkGeneric 02/2015 - 08/2011
9	CalciumIBA 03/2024 - 08/2011
9	Neprilysin (Neutral Endopeptidase)IBA 11/2023 - 10/2015
9	Mineralocorticoid Receptor AntagonistsIBA 11/2023 - 02/2015
9	Angiotensin Receptors (Angiotensin II Receptor)IBA 11/2023 - 10/2015
9	aliskiren FDA Link 01/2023 - 02/2012
9	LipidsIBA 09/2021 - 02/2005
9	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 02/2008 - 11/2003
8	Influenza Vaccines (Influenza Vaccine)FDA Link 05/2024 - 01/2019
8	CreatinineIBA 12/2023 - 02/2005
8	Angiotensin Receptor AntagonistsIBA 01/2022 - 05/2013
8	Carvedilol (Coreg)FDA LinkGeneric 01/2021 - 02/2005
8	Anti-Arrhythmia AgentsIBA 08/2011 - 01/2002
7	Metformin (Glucophage)FDA LinkGeneric 06/2024 - 08/2011
7	Enalapril FDA LinkGeneric 01/2023 - 10/2014
6	Anti-Bacterial Agents (Antibiotics)IBA 05/2024 - 01/2013
6	Ramipril (Altace)FDA LinkGeneric 03/2024 - 11/2021

Therapy/Procedure

112	Therapeutics 05/2024 - 01/2002
70	Percutaneous Coronary Intervention 03/2024 - 12/2007
38	Implantable Defibrillators (Implantable Cardioverter-Defibrillator) 05/2024 - 11/2004
23	Resuscitation 11/2022 - 08/2009
18	Drug Therapy (Chemotherapy) 05/2024 - 08/2007
15	Home Nursing (Nursing, Home) 11/2023 - 03/2014
13	Induced Hypothermia 01/2018 - 10/2010
12	Stents 11/2023 - 04/2006
12	Defibrillators (Defibrillator) 01/2023 - 09/2005
12	Cardiopulmonary Resuscitation (CPR) 12/2020 - 08/2010
11	Patient Readmission 04/2024 - 09/2003
11	Transcatheter Aortic Valve Replacement 12/2023 - 07/2020
8	Coronary Artery Bypass (Coronary Artery Bypass Surgery) 11/2022 - 12/2007
7	Cardiac Resynchronization Therapy 10/2023 - 01/2006